A method for the differential diagnosis of meningitis by determining the cytokine profile using a rapid measurement device at point of care

Coordinated by: Florin Babarada

Other department members involved in this project: Miron Cristea, Horia Cucu, Mariana Ilaş, Lucian Petrică, Gheorghe Pristavu, Ovidiu Profirescu, Cristian Ravariu

Other persons involved in the project

Andi Buzo
Topor Alexandru
Mălin Ștefan

Description:

Tissue regeneration involves many promoters/factors. Cytokines are secreted by many cell types and function as signalling molecules. They also promote and/or prevent cell adhesion, proliferation, migration, and differentiation by up- or down-regulating the synthesis of proteins, growth factors, and receptors.
Numerous studies have investigated how cell gene expression and protein production respond to electrical signals of varying amplitude and frequency. The release of growth factors and cytokines from bone cells is critical to both bone formation and turnover.
The project realized a medical sensor device for cytokine profile determination. Design of the device was done with TCAD 3D software. In later phases, with our medical partners, a method for the differential diagnosis of meningitis by using the designed device to determine the cytokine profile using a rapid measurement device at point of care was realized.

Partener (P1) - C.Y.B.E.R. SRL
Partener (P2) - Spitalul Clinic de Boli Infectioase si Tropicale "Dr. Victor Babes"
Partener (P3) - Universitatea POLITEHNICA din Bucuresti